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Buy Melanotan 10MG Online ; Melanotan produces its photoprotective effects by triggering a ‘signaling cascade’ via its activation of the MC1R on melanin-producing cells known as melanocytes.
In addition Upon Melanotan binding with the MC1R on the surface of melanocytes in the epidermal layer of the skin. it begins a series of actions and reactions that result in melanocytes favoring the production of eumelanin (photoprotective black/brown pigment).
Buy Melanotan 2&MT1 10MG Online; Furthermore CAMP in turn activates protein kinase A (PKA) resulting in the phosphorylation of the cAMP response element-binding (CREB). Phosphorylated CREB will bind to the cAMP response element (CRE) on the microphthalmia-associated transcription factor (MITF) gene leading to the synthesis of the MITF protein.
Buy Melanotan 2&MT1 10MG Online; MITF has the ability to activate several genes by binding to them, including the MC1R gene and the genes involved in melanogenesis. This results in increased concentrations of the melanogenic enzymes within the melanocyte.
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