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Therapeutic indications: Also For the treatment of moderate to severe pain in patients with cancer and post-operative pain. That is to say For the treatment of severe pain requiring the use of a strong opioid.
– Posology and method of administration
OxyContin tablets should be taken at 12-hourly intervals. The dosage is dependent on the severity of the pain, and the patient’s previous history of analgesic requirements.
OxyContin is not intended for use as a prn analgesic.
BBuy Oxycodone 80mg Online; Increasing severity of pain will require an increase dosage of OxyContin tablets, using the 5 mg, 10 mg, 20 mg, 40 mg or 80 mg tablet strengths, either alone or in combination, to achieve pain relief. The correct dosage for any individual patient is that which controls the pain and is well tolerate for a full 12 hours.
Patients should be titrate to pain relief unless unmanageable adverse drug reactions prevent this. The need for escape medication more than twice a day indicates that the dosage of OxyContin tablets should be increase.
The usual starting dose for opioid naïve patients or patients presenting with severe pain uncontrol by weaker opioids is 10 mg, 12-hourly. Some patients may benefit from a starting dose of 5 mg to minimize the incidence of side effects.
The dose should then be carefully titrate, as frequently as once a day if necessary, to achieve pain relief. For the majority of patients, the maximum dose is 200 mg 12-hourly. However, a few patients may require higher doses. Doses in excess of 1000 mg daily have been record.
Conversion from oral morphine:
Buy Oxycodone 80mg online; Patients receiving oral morphine before OxyContin therapy should have their daily dose base on the following ratio: 10 mg of oral oxycodone is equivalent to 20 mg of oral morphine. It must be emphasis that this is a guide to the dose of OxyContin tablets require. Inter-patient variability requires that each patient is carefully titrat to the appropriate dose.
Buy Oxycodone 80mg Online; A dose adjustment is not usually necessary in elderly patients. Controlled pharmacokinetic studies in elderly patients (aged over 65 years) have shown that, compared with younger adults, the clearance of oxycodone is only slightly reduce.